UWA Handbook 2017

Unit details

BIOC3353 Molecular and Structural Biochemistry Part 1

Credit 12 points
(see Timetable)
Offshore teaching periodSingaporeon-campus
Content This unit builds on what is taught at Level 2 in BIOC2201 Biochemistry of the Cell, BIOC2202 Biochemical Regulation of Cell Function and SCIE2225 Molecular Biology, and addresses cellular function from the perspective of the cellular macromolecules—DNA, RNA and protein. The relationship between structure and function is emphasised throughout the unit. Accordingly, how transcription and differential gene expression are accomplished in terms of the structure of DNA and RNA is addressed. How protein structure is studied, the established structural features of simple and complex proteins and how these relate to protein and enzyme function form a major component of the unit. This unit does not aim to be comprehensive in its coverage, but aims to select areas in these fields that are currently making an impact on biomedical science. Recent advances are highlighted and publications are discussed in the tutorials. Accordingly, they provide the biochemical basis for advanced units in molecular biology and cell biology. The unit does not duplicate, but complements, the content of SCIE3326/SCIE3327 Molecular Biology Part 1/Part 2. Laboratory work comprises experiments designed to teach the major biochemical techniques: protein purification, electrophoresis, protein mass spectrometry and metabolite assays. The design, logistics and analysis of experiments are also emphasised.
Outcomes Students gain an understanding of cellular function from the perspective of the cellular macromolecules—DNA, RNA and protein; and are able to carry out a range of modern biochemical techniques used with macromolecules.
Assessment This unit comprises an end-of-semester examination (40 per cent), a mid-semester examination (15 per cent), a journal club presentation (7.5 per cent), laboratory assessment (30 per cent) and a sequence analysis—molecular modelling assignment (7.5 per cent).

Supplementary assessment is not available in this unit except in the case of a bachelor's pass degree student who has obtained a mark of 45 to 49 and is currently enrolled in this unit, and it is the only remaining unit that the student must pass in order to complete their course.
Unit Coordinator(s) Professor Paul Attwood and Associate Professor Robert Tuckey
Unit rules
Prerequisites: BIOC2201 Biochemistry of the Cell and BIOC2202 Biochemical Regulation of Cell Function
Advisable prior study: SCIE2225 Molecular Biology and a Level 2 chemistry unit
Incompatibility: BIOC3371 Molecular and Structural Biochemistry
Contact hours lectures: 36 hours; tutorials: 6 hours; labs: 60 hours
Unit Outlinehttp://www.unitoutlines.science.uwa.edu.au/Units/BIOC3353/TS-OFF-G3/2017

  • The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
  • All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
  • Books and other material wherever listed may be subject to change. Book lists relating to 'Preliminary reading', 'Recommended reading' and 'Textbooks' are, in most cases, available at the University Co-operative Bookshop (from early January) and appropriate administrative offices for students to consult. Where texts are listed in the unit description above, an asterisk (*) indicates that the book is available in paperback.