UWA Handbook 2017

Unit details

PHCY5610 Physical Pharmacy and Biopharmaceutics

Credit 6 points
  Offering
(see Timetable)
AvailabilityLocationMode
Semester 1UWA (Perth)Face to face
Content This is a foundation unit in the Master of Pharmacy course. It provides an overview of the principles of physical pharmacy, pharmaceutical calculations and biopharmaceutics that underpin drug formulation into acceptable dosage forms and their therapeutic outcomes. The physical pharmacy and biopharmaceutics concepts are delivered through a combination of lectures and tutorials. Students apply this knowledge in tutorials and 'Drug of the Week' seminars. The latter provides a forum to discuss common drugs sold and supplied in community pharmacies. Students also learn to apply mathematical principles to calculate drug doses and the extemporaneous compounding of pharmaceutical formulations through case-based exercises in tutorials and practical classes.
Outcomes Students are able to (1) explain and apply the key physical pharmacy concepts of acid-base ionisation, solubility and dissolution, partitioning phenomena, surface phenomena, colloid properties and powder properties; (2) articulate the interrelationships between the physiochemical properties of a drug, its dosage form, route of administration and bioavailability; (3) recognise common pharmaceutical surfactants and apply them to enhance drug solubility, dissolution and bioavailabilty; (4) classify a drug into its biopharmaceutical class and predict its bioavailability; (5) understand, differentiate and apply the concepts of bioavailability and bioequivalence; (6) apply mathematical principles to the preparation and the safe and effective use of medicinal products in different patient populations; (7) prepare, label and record the extemporisation of medicinal mixtures in compliance with legislative and professional practice frameworks; and (8) review drugs sold and supplied in community pharmacies.
Assessment Typically this unit is assessed in the following ways: (1) cumulative calculation assessments (10 per cent); (2) summative assessment (20 per cent); (3) laboratory assessment (10 per cent); (4) oral assessment (10 per cent); and (5) final written examination (50 per cent). Further information is available in the unit outline.

Supplementary assessment is available for those students who obtain a mark of 45 to 49 inclusive in this unit.
Unit Coordinator(s) Professor Lee Yong Lim
Unit rules
Prerequisites: enrolment in the Master of Pharmacy
Contact hours lectures: 4 hours per week for 10 weeks; tutorials: 4 hours per week for 6 weeks and 2 hours for 1 week; labs: 4 hours per week for 4 weeks and 2 hours for 1 week; seminar presentations: 4 hours per week for 2 weeks
Unit Outlinehttp://www.unitoutlines.meddent.uwa.edu.au/Units/PHCY5610/SEM-1/2017
Texts

Aulton, M, Pharmaceutics: The design and manufacture of Medicines, 4th edn, Churchill Livingstone, 2013

Ansel, H, Pharmaceutical Calculations, 14th edn, Wolters Kluwer Health/Lippincott William & Wilkins

The Australian Pharmaceutical Formulary and Handbook, current edn, Pharmaceutical Society of Australia


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