UWA Handbook 2017

Unit details

PUBH5742 Fundamentals of Genetic Epidemiology

Credit 6 points
  Offering
(see Timetable)
AvailabilityLocationMode
Not available in 2017UWA (Perth)Face to face
Content This is an introductory unit covering background and methods relevant to the analysis of genetic data in epidemiological studies, with emphasis on gene mapping. Topics covered include basic population genetics, familial aggregation analysis, linkage analysis, family and population based association analyses, haplotypic analysis, and study designs for gene discovery in complex human diseases. Students gain exposure to some of the methods and computer tools available for gene mapping and genetic analysis, and begin to read and evaluate genetic epidemiological literature.
Outcomes Students are able to (1) possess an overview of the current state-of-the-art in genetic epidemiology, sufficient to critically interpret the literature on gene discovery in complex human disease; (2) understand the biological and statistical principles underlying modern gene discovery, and the research methods for the study of genetic risk factors in epidemiology; (3) understand sources of error in genetic epidemiology, the difference between confounding and effect modification in genetics, and the strengths and limitations of the available study designs for genetic epidemiological research; (4) perform basic statistical analyses on genetic data including family-based association analyses, and haplotypic analysis; (5) understand the public health applications of complex disease genetics; and (6) write a report on a study in 'genetics' format.
Assessment Typically this unit is assessed in the following ways: (1) two take-home narrative assignments; (2) a class project involving hands-on computing and analysis; and (3) a final take-home hands-on assignment. Further information is available in the unit outline.

Supplementary assessment is not available in this unit.
Unit Coordinator(s) Dr Phillip Melton
Unit rules
Advisable prior study: PUBH4403 Epidemiology I, PUBH4401 Biostatistics I

  • The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
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  • Books and other material wherever listed may be subject to change. Book lists relating to 'Preliminary reading', 'Recommended reading' and 'Textbooks' are, in most cases, available at the University Co-operative Bookshop (from early January) and appropriate administrative offices for students to consult. Where texts are listed in the unit description above, an asterisk (*) indicates that the book is available in paperback.