PATH5151 Molecular Pathology

6 points
(see Timetable)
Semester 2UWA (Perth)Face to face
This unit provides students with the basic principles of the role of genetic factors in the causation of human disease. The emphasis is on molecular genetics, especially in the areas of diagnosis, prognosis, prevention of disease and their application to clinical medicine. Incorporating the principles of chromosome structure and function, patterns of inheritance, population genetics, single gene disorders, multifactorial diseases, chromosomal and somatic cell genetic disorders, mitochondrial diseases and pre-natal diagnosis the unit delivers practical skills focused on screening methods for genetic abnormalities, assessment of risk status and coverage of the basics of clinical cytogenetics, pharmacogenetics and those aspects of immunogenetics that relate to tissue transplantation programs. Analysis and interpretation of data drawn from routine clinical laboratory practice enables students to demonstrate their understanding of these subject areas.
Students are able to (1) discuss the organisation of genomes and other important genetic structures; (2) explain genomic variation and inheritance; (3) conduct specific genetic tests relevant to clinical practice; (4) explain the role of pharmacogenetics in personalised medicine; (5) interpret the results of analytical techniques used for mutation detection; and (6) demonstrate an understanding of biochemical and cancer genetics.
Indicative assessments in this unit are as follows: (1) practical reports; (2) a seminar; and (3) examinations. Further information is available in the unit outline.

Supplementary assessment is not available in this unit.
Unit Coordinator(s)
Dr Clayton Fragall
Unit rules
Enrolment in the Master of Clinical Pathology 92510
other relevant postgraduate degree as determined by the Faculty.
Contact hours
lectures: 2 hours per week; tutorials/labs/workshops: 4-5 hours per week
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