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Unit Overview

Description

This unit explores the molecular mechanisms that underpin gene function and regulation, with a focus on genetic variation, mutation, and foundational genomic technologies. Students will gain insights into the functional consequences of genetic variation, molecular mechanisms of gene mutation and repair, and how genomic techniques are used to map disease genes and understand complex traits. The integration of case studies, real-world applications, laboratory and bioinformatics skills equips students with key insights into functional genomics and its relevance to health and disease.

Credit
6 points
Offering
AvailabilityLocationModeFirst year of offer
Not available in 2025UWA (Perth)Face to face
Outcomes

Students are able to (1) explain the causes and consequences of gene mutations, describing the underlying mechanisms and evaluating DNA repair processes; (2) describe the principles of epigenetic regulation, including the mechanisms that influence gene expression and patterns of inheritance; (3) apply foundational molecular techniques to investigate genetic variation, including the use of sequencing technologies and genetic databases; (4) integrate knowledge of linkage analysis and genome-wide association studies to explore the genetic basis of complex human diseases; and (5) acquire technical skills applicable to the molecular sciences.

Assessment

Indicative assessments in this unit are as follows: (1) exam; (2) in semester-tests; and (3) workshop/practical assessments. Further information is available in the unit outline.



Student may be offered supplementary assessment in this unit if they meet the eligibility criteria.

Unit Coordinator(s)
Dr Belinda Kaskow
Unit rules
Prerequisites
Successful completion of
SCIE1106 Molecular Biology of the Cell
Incompatibility
GENE2230 Molecular Genetics I Students enrolled in both MJD-GENET and MJD-HUMGE may chose either GENE2230
OR GENE2210
Contact hours
Up to 2 lectures per week, Workshops: 4 x 2 hours and Practicals: 4 x 3 hours
  • The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
  • All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
  • Visit the Essential Textbooks website to see if any textbooks are required for this Unit. The website is updated regularly so content may change. Students are recommended to purchase Essential Textbooks, but a limited number of copies of all Essential Textbooks are held in the Library in print, and as an ebook where possible. Recommended readings for the unit can be accessed in Unit Readings directly through the Learning Management System (LMS).
  • Contact hours provide an indication of the type and extent of in-class activities this unit may contain. The total amount of student work (including contact hours, assessment time, and self-study) will approximate 150 hours per 6 credit points.