PATH3304 Drugs and Disease B

Credit
6 points
Offering
(see Timetable)
AvailabilityLocationMode
Semester 2QEII Medical CentreFace to face
Details for undergraduate courses
  • Level 3 elective
Content
This unit aims primarily to develop skills in reasoning in pathology and pharmacology, calling on pre-existing knowledge of physics, chemistry and biology and new knowledge in pathology and pharmacology. Both PHAR3303 Drugs and Disease A and this unit use examples of human disease where the origins, pathogenesis and treatment of the disease have now been well revealed by research. It is envisaged that this unit uses the respiratory system, musculoskeletal system, blood and immune system and breast and prostate to illustrate disease mechanisms associated with infections, immune-mediated disease, inflammation and cancer and the therapies used to treat those diseases. The unit uses these model diseases to develop in students an understanding of the reasoning processes that underlie the discipline of pathology and which guide the development of treatments including drugs. Students learn how understanding disease pathogenesis reveals targets for curative or preventative treatments.
Outcomes
Students are able to (1) describe, by use of examples, how an understanding of disease reveals targets for drug action at molecular, cellular and tissue levels; (2) by reference to specific examples, describe how disease processes influence the magnitude, direction and duration of drug actions in the body, both beneficially and adversely; (3) by reference to specific examples, describe how disease not only creates targets for beneficial drug intervention but also lays open physiological processes for disruption, leading to adverse drug effects; (4) describe specific examples where disease itself, as well as the genetic and environmental factors that lead to it, dictates drug choice by creating specific drug responsiveness or toxicity; (5) describe the main stages in the process whereby molecules turn into medicines for the specific disease examples studied in the course; (6) develop skills in the acquisition and communication (both written and verbal) of scientifically robust information on the interplay of pathology and pharmacology in a particular disease process; and (7) further develop skills needed in the execution of simple laboratory procedures relevant to assessing the actions of drugs in disease.
Assessment
Indicative assessments in this unit are as follows: (1) mid-semester assessment; (2) laboratory reports and communications; and (3) end-of-semester examination. Further information is available in the unit outline.

Supplementary assessment is not available in this unit except in the case of a bachelor's pass degree student who has obtained a mark of 45 to 49 overall and is currently enrolled in this unit, and it is the only remaining unit that the student must pass in order to complete their course.
Unit Coordinator(s)
Assistant Professor Clayton Fragall
Unit rules
Prerequisites:
Biomedical Science major Level 2 units
Incompatibility:
PHAR2220 Human Pharmacology, PHAR3310 Molecular Pharmacology, PHAR3311 Molecular Pharmacology Methods, PATH3306 Integrated and Applied Pathology, PATH3302 Pathology: Human Oncobiology, PATH3305 Medical Genetics, PATH3354 Immunology and Immunopathology, PATH3308 Pathology and Laboratory Medicine II
Contact hours
lectures: 2 hours per week; practical sessions: 1 per fortnight; research and communication skills workshop
Texts

Book lists are available from the University Co-operative Bookshop and Pathology Office for students to consult.

  • The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
  • All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
  • Books and other material wherever listed may be subject to change. Book lists relating to 'Preliminary reading', 'Recommended reading' and 'Textbooks' are, in most cases, available at the University Co-operative Bookshop (from early January) and appropriate administrative offices for students to consult. Where texts are listed in the unit description above, an asterisk (*) indicates that the book is available in paperback.