PHCY5611 Medicinal Product Formulation
- 6 points
If this unit does not have an online alternative, then students who are presently unable to enter Western Australia and whose studies would be delayed by an inability to complete this unit, should contact the unit coordinator (details given on this page) to ascertain, on an individual case-by-case basis, if alternate arrangements can be made to support their study in this unit.
Availability Location Mode Semester 2 UWA (Perth) Multi-mode Multiple modes of delivery. Unit includes a mix of online and on-campus study requirements. On campus attendance for some activities is required to complete this unit.
- This unit introduces students to the principles and processes of medicinal product formulation and production. Building on the foundations delivered in PHCY5610 Physical Pharmacy and Biopharmaceutics, this unit brings students through the formulation and production of major solid, semi-solid, liquid, aerosolised and controlled release drug formulations. Students are provided with an overview of common pharmaceutical excipients, and the principles for preservation, sterilisation and packaging of medicinal products. Tutorials require students to apply the formulation principles to discuss and resolve issues in case-based medicinal product development. The preparation of some medicinal products is undertaken in the laboratory with emphasis on both the science and art of extemporaneous compounding within legislative and professional practice frameworks. Students are also provided opportunities to visit TGA-approved, Perth-based manufacturing facilities of medicinal products. The focus, as in all the pharmacy units, is on the delivery of optimum patient care.
- Students are able to (1) compare and contrast solid, semi-solid, liquid and aerosolised medicinal products and evaluate the appropriateness of their use in clinical settings; (2) evaluate the categories of pharmaceutical excipients, naming two to three examples in each category, that are required for the manufacture of specific medicinal products; (3) analyse the pharmaceutical principles underpinning the manufacture of safe and efficacious medicinal products; (4) analyse the means for achieving and validating the preservation and sterilisation of medicinal products; (5) demonstrate an advanced understanding of the principles for proper handling and disposal of cytotoxic medicinal products; (6) analyse the Therapeutic Goods Administration requirements for authorised medicinal products; (7) demonstrate an advanced understanding of the principles of Good Manufacturing Practice; (8) compare and contrast the packaging materials used for medicinal products; (9) apply mathematical principles to the preparation, and the safe and effective use of medicinal products in different patient populations; (10) prepare, label and record the extemporisation of a range of medicinal products in compliance with legislative and professional practice frameworks; and (11) demonstrate an advanced understanding of dosage form preferences in diverse patient groups (age, cultural, rural).
- Indicative assessments in this unit are as follows: (1) ongoing assessments; (2) laboratory assessments; and (3) final written examination. Further information is available in the unit outline.
Supplementary assessment is not available in this unit.
- Unit Coordinator(s)
- Professor Lee Yong Lim
- Unit rules
- enrolment in the Master of Pharmacy (51500)
- Contact hours
- lectures and tutorials: 4 hours x 12 weeks; labs: 27 hours; site visits: 1.5 hours
Aulton, M. Pharmaceutics: The Design and Manufacture of Medicines, current edn: Churchill Livingstone
Australian Pharmaceutical Formulary and Handbook, current edn: Pharmaceutical Society of Australia
- The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
- All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
- Unit readings, including any essential textbooks, are listed in the unit outline for each unit, one week prior the commencement of study. The unit outline will be available via the LMS and the UWA Handbook one week prior the commencement of study. Reading lists and essential textbooks are subject to change each semester. Information on essential textbooks will also be made available on the Essential Textbooks. This website is updated regularly in the lead up to semester so content may change. It is recommended that students purchase essential textbooks for convenience due to the frequency with which they will be required during the unit. A limited number of textbooks will be made available from the Library in print and will also be made available online wherever possible. Essential textbooks can be purchased from the commercial vendors to secure the best deal. The Student Guild can provide assistance on where to purchase books if required. Books can be purchased second hand at the Guild Secondhand bookshop (second floor, Guild Village), which is located on campus.