PHCY5611 Medicinal Product Formulation
- 6 points
Availability Location Mode Semester 2 UWA (Perth) Face to face
- This unit introduces students to the principles and processes of medicinal product formulation and production. Building on the foundations delivered in PHCY5610 Physical Pharmacy and Biopharmaceutics, this unit brings students through the formulation and production of major solid, semi-solid, liquid, aerosolised and controlled release drug formulations. Students are provided with an overview of common pharmaceutical excipients, and the principles for preservation, sterilisation and packaging of medicinal products. Tutorials require students to apply the formulation principles to discuss and resolve issues in case-based medicinal product development. The preparation of some medicinal products is undertaken in the laboratory with emphasis on both the science and art of extemporaneous compounding within legislative and professional practice frameworks. Students are also provided opportunities to visit TGA-approved, Perth-based manufacturing facilities of medicinal products. The focus, as in all the pharmacy units, is on the delivery of optimum patient care.
- Students are able to (1) define and differentiate between solid, semi-solid, liquid and aerosolised medicinal products and evaluate the appropriateness of their use in clinical settings; (2) identify the categories of pharmaceutical excipients, naming two to three examples in each category, that are required for the manufacture of specific medicinal products; (3) discuss the pharmaceutical principles underpinning the manufacture of safe and efficacious medicinal products; (4) outline the means for achieving and validating the preservation and sterilisation of medicinal products; (5) understand the principles for proper handling and disposal of cytotoxic medicinal products; (6) articulate the Therapeutic Goods Administration requirements for authorised medicinal products; (7) understand the principles of Good Manufacturing Practice; (8) compare and contrast the packaging materials used for medicinal products; (9) apply mathematical principles to the preparation, and the safe and effective use of medicinal products in different patient populations; (10) prepare, label and record the extemporisation of a range of medicinal products in compliance with legislative and professional practice frameworks; and (11) be aware of dosage form preferences in diverse patient groups (age, cultural, rural).
- Indicative assessments in this unit are as follows: (1) ongoing assessments; (2) laboratory assessments; and (3) final written examination. Further information is available in the unit outline.
Supplementary assessment is not available in this unit.
- Unit Coordinator(s)
- Professor Lee Yong Lim
- Unit rules
- enrolment in the Master of Pharmacy (51500)
- Contact hours
- lectures and tutorials: 4 hours x 12 weeks; labs: 4 hours x 8 weeks; site visits: 1.5 hours x 2 weeks
Aulton, M. Pharmaceutics: The Design and Manufacture of Medicines, current edn: Churchill Livingstone
Australian Pharmaceutical Formulary and Handbook, current edn: Pharmaceutical Society of Australia
- The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
- All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
- Books and other material wherever listed may be subject to change. Book lists relating to 'Preliminary reading', 'Recommended reading' and 'Textbooks' are, in most cases, available at the University Co-operative Bookshop (from early January) and appropriate administrative offices for students to consult. Where texts are listed in the unit description above, an asterisk (*) indicates that the book is available in paperback.