Studying online
There are now 2 possible online modes for units:
Units with modes Online timetabled and Online flexible are available for any student to self-enrol and study online.
Click on an offering mode for more details.
Unit Overview
- Description
This unit introduces the concepts necessary for an appreciation of medicinal chemistry, thereby providing a solid background for further study and employment in the drug discovery industry. The syllabus begins with an overview of drugs and medicinal chemistry and then considers the pharmacodynamic and pharmacokinetic properties essential for useful drugs, including a survey of biological (macromolecular) targets, the energetics of drug target interactions, molecular recognition, absorption, distribution, metabolism and excretion (ADME). The process of drug discovery and design is explored, beginning with factors affecting choice of disease/biological target, the discovery of lead compounds and then progressing to principles and strategies for drug optimisation including analogue design, structure activity relationships, structure-based drug design, reducing side-effects and improving bioavailability including pro-drug strategies.
- Credit
- 6 points
- Outcomes
Students learn the key concepts and principles involved in medicinal chemistry including the essential role of chemists in the drug discovery process. Laboratory skills are enhanced by practical exercises relevant to medicinal chemistry including synthetic chemistry, chromatography, basic bioassays, measurement of physiochemical properties relevant to pharmacokinetics and combinatorial chemistry.
- Assessment
This comprises laboratory (30 per cent), a mid-semester examination (30 per cent), an oral presentation (10 per cent) and a final examination (30 per cent).
Student may be offered supplementary assessment in this unit if they meet the eligibility criteria.
- Unit Coordinator(s)
- Associate Professor Matthew Piggott
- Unit rules
- Contact hours
- lectures: 26 x 1 hour
labs: 36 hours - Texts
Patrick, G. L. An Introduction to Medicinal Chemistry, 3rd edn: OUP 2005
- The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
- All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
- Unit readings, including any essential textbooks, are listed in the unit outline for each unit, one week prior the commencement of study. The unit outline will be available via the LMS and the UWA Handbook one week prior the commencement of study. Reading lists and essential textbooks are subject to change each semester. Information on essential textbooks will also be made available on the Essential Textbooks. This website is updated regularly in the lead up to semester so content may change. It is recommended that students purchase essential textbooks for convenience due to the frequency with which they will be required during the unit. A limited number of textbooks will be made available from the Library in print and will also be made available online wherever possible. Essential textbooks can be purchased from the commercial vendors to secure the best deal. The Student Guild can provide assistance on where to purchase books if required. Books can be purchased second hand at the Guild Secondhand bookshop (second floor, Guild Village), which is located on campus.
- Contact hours provide an indication of the type and extent of in-class activities this unit may contain. The total amount of student work (including contact hours, assessment time, and self-study) will approximate 150 hours per 6 credit points.
Face to face
Predominantly face-to-face. On campus attendance required to complete this unit. May have accompanying resources online.
Online flexible
100% Online Unit. NO campus face-to-face attendance is required to complete this unit. All study requirements are online only. Unit is asynchronous delivery, with NO requirement for students to participate online at specific times.
Online timetabled
100% Online Unit. NO campus face-to-face attendance is required to complete this unit. All study requirements are online only. Unit includes some synchronous components, with a requirement for students to participate online at specific times.
Online Restricted
Not available for self-enrolment. Students access this mode by contacting their student office through AskUWA. 100% Online Unit.
NO campus face-to-face attendance. All study and assessment requirements are online only. Unit includes some timetabled activities, with a requirement for students to participate online at specific times. In exceptional cases (noted in the Handbook) students may be required to participate in face-to-face laboratory classes when a return to UWA’s Crawley campus becomes possible in order to be awarded a final grade.
External
No attendance or regular contact is required, and all study requirements are completed either via correspondence and/or online submission.
Off-campus
Regular attendance is not required, but student attends the institution face to face on an agreed schedule for purposes of supervision and/or instruction.
Multi-mode
Multiple modes of delivery. Unit includes a mix of online and on-campus study requirements. On campus attendance for some activities is required to complete this unit.