PHCY5610 Physical Pharmacy and Biopharmaceutics

6 points
(see Timetable)
Non-standard teaching periodUWA (Perth)Face to face
This is a foundation unit in the Master of Pharmacy course. It provides an overview of the principles of physical pharmacy, pharmaceutical calculations and biopharmaceutics that underpin drug formulation into acceptable dosage forms and their therapeutic outcomes. The physical pharmacy and biopharmaceutics concepts are delivered through a combination of lectures and tutorials. Students apply this knowledge in tutorials. Students also learn to apply mathematical principles to calculate drug doses and the extemporaneous compounding of pharmaceutical formulations through case-based exercises in tutorials and practical classes.
Students are able to (1) explain and apply the key physical pharmacy concepts of acid-base ionisation, solubility and dissolution, partitioning phenomena, surface phenomena, colloid properties and powder properties; (2) articulate the interrelationships between the physiochemical properties of a drug, its dosage form, route of administration and bioavailability; (3) recognise common pharmaceutical surfactants and apply them to enhance drug solubility, dissolution and bioavailabilty; (4) classify a drug into its biopharmaceutical class and predict its bioavailability; (5) understand, differentiate and apply the concepts of bioavailability and bioequivalence; (6) apply mathematical principles to the preparation and the safe and effective use of medicinal products in different patient populations; and (7) prepare, label and record the extemporisation of medicinal mixtures in compliance with legislative and professional practice frameworks.
Indicative assessments in this unit are as follows: (1) ongoing assessments; (2) laboratory assessment; and (3) final written examination. Further information is available in the unit outline.

Supplementary assessment is available for students currently enrolled in the unit who obtain a mark of 45 to 49 overall.
Unit Coordinator(s)
Professor Lee Yong Lim
Unit rules
enrolment in the Master of Pharmacy
Contact hours
lectures: 4 hours per week for 10 weeks; tutorials: 4 hours per week for 6 weeks and 2 hours for 1 week; labs: 4 hours per week for 4 weeks and 2 hours for 1 week
Unit Outline
Non-standard teaching period [TS-K-1-2020]

Aulton, M, Pharmaceutics: The design and manufacture of Medicines, current edn, Churchill Livingstone.

Ansel, H, Pharmaceutical Calculations, current edn, Wolters Kluwer Health/Lippincott William & Wilkins

The Australian Pharmaceutical Formulary and Handbook, current edn, Pharmaceutical Society of Australia

  • The availability of units in Semester 1, 2, etc. was correct at the time of publication but may be subject to change.
  • All students are responsible for identifying when they need assistance to improve their academic learning, research, English language and numeracy skills; seeking out the services and resources available to help them; and applying what they learn. Students are encouraged to register for free online support through GETSmart; to help themselves to the extensive range of resources on UWA's STUDYSmarter website; and to participate in WRITESmart and (ma+hs)Smart drop-ins and workshops.
  • Books and other material wherever listed may be subject to change. Book lists relating to 'Preliminary reading', 'Recommended reading' and 'Textbooks' are, in most cases, available via the Booktopia Textbook Finder, which has the functionality to search by course code, course, ISBN and title, and may also be posted or available at the appropriate school's administrative offices. Where texts are listed in the unit description above, an asterisk (*) indicates that the book is available in paperback.