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PHCY5630 Integrated Pharmacology, Therapeutics and Pharmacy Practice 3

6 points
(see Timetable)
Non-standard teaching periodUWA (Perth)Face to face
This unit continues to provide detailed pharmacology and pharmacotherapy of major disease states and further expands on the concepts and application of pharmacokinetics, which is first introduced to students in PHCY5602 Pharmacy Practice and Pharmacotherapy 1. An emphasis is placed on the student increasing their awareness of the patient as a whole through the concept of patient centred care.

Pharmacology and pharmacotherapy is presented in an integrated fashion and will provide an in-depth look at the pharmacists' role in the management of major disease states.

Other topics include drug interactions; therapeutic drug monitoring; laboratory testing and monitoring of results; sources of inter-patient variability in pharmacokinetics, clinical case studies and pharmacokinetics of specific drugs.

A case-based approach to learning helps student focus is on the key learning objectives. The cases are selected so that they challenge the students' understanding of the topic and provide ground for discussion between the student and the topic tutor. Use of clinically-oriented problems and case studies will enable students to apply principles of pharmacology and pharmacotherapy to real-world examples in preparation for hospital placements.
Students are able to (1) describe the mechanism of action, pharmacological effects, pharmacokinetic properties, therapeutic uses, contraindications, adverse effects and clinically significant drug interactions of the principal drugs and drug classes used to treat various conditions; (2) use knowledge of pharmacological principles and major disease states to make clinical decisions about patient care; (3) explain how interference with absorption, distribution, metabolism and elimination can lead to clinically important drug interactions and predict potential drug interactions from a working knowledge of their metabolic pathway; (4) discuss the principles of pharmacokinetics in special populations (such as paediatrics, elderly or obese patients); (5) use pharmacokinetic and pharmacodynamic principles in cases using patient data, to optimise pharmacotherapy for maximal efficacy and minimal toxicity; (6) demonstrate an understanding of the key concepts of toxicology; and (7) interpret common laboratory test results and apply these to clinical scenarios.
Indicative assessments in this unit are as follows: (1) ongoing assessments; (2) oral assessment; and (3) written examination. Further information is available in the unit outline.

To pass this unit, a student must: (a) achieve an overall mark of 50 per cent or higher for the unit; and (b) achieve the requisite requirements(s) or a mark of 50 per cent or greater, whichever is higher and specified in the unit outline, for the oral assessment component.

Student may be offered supplementary assessment in this unit if they meet the eligibility criteria.
Unit Coordinator(s)
Associate Professor Philip Burcham & Dr Sandra Salter
Unit rules
51500 Master of Pharmacy (ID 123) and PHCY5615 Pharmacy Placement I (ID 2813)
PHCY5612 Integrated Pharmacology, Therapeutics and Pharmacy Practice 2 (ID 3719)
Contact hours
Lectures and workshop: 4 hours per week; tutorials: 2 hours per week

Required texts
1. Australian Pharmaceutical Formulary and Handbook. Current edition. PSA.
2. Australian Medicines Handbook. Current edition. PSA.

Recommended texts
Chen, T et al. Case Studies in Practice - Medication Review: A Process Guide for Pharmacists. Current edition. PSA.

Chen, T et al. Case Studies in Practice. Pharmacist only and pharmacy medicines: a process guide for pharmacists. Current edition. PSA.

DiPiro J et al. Concepts in Clinical Pharmacokinetics. Current edition. American Society of Health-System Pharmacy.

Gowan J and Roller L. Practical disease state management for pharmacists. Current edition. APPCo.

Hughes, J. Case Studies in Practice. Use of Laboratory Test Data. Current edition. PSA.

Kumar V, Abbas AK, Fausto N, AsterJ.  Robbins and Cotran Pathologic basis of disease. Current edition. Elsevier Health Sciences‎

Rang, H et al. Rang and Dale’s Pharmacology. Current edition. Elsevier

Tozer et al. Essentials of Pharmacokinetics and Pharmacodynamics. Current edition. Lippincott, Williams & Wilkins

Walker, R and Edwards, C. Clinical Pharmacy and Therapeutics. Churchill Livingstone. Current edition.

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  • Unit readings, including any essential textbooks, are listed in the unit outline for each unit, one week prior the commencement of study. The unit outline will be available via the LMS and the UWA Handbook one week prior the commencement of study. Reading lists and essential textbooks are subject to change each semester. Information on essential textbooks will also be made available on the Essential Textbooks. This website is updated regularly in the lead up to semester so content may change. It is recommended that students purchase essential textbooks for convenience due to the frequency with which they will be required during the unit. A limited number of textbooks will be made available from the Library in print and will also be made available online wherever possible. Essential textbooks can be purchased from the commercial vendors to secure the best deal. The Student Guild can provide assistance on where to purchase books if required. Books can be purchased second hand at the Guild Secondhand bookshop (second floor, Guild Village), which is located on campus.